The fatty acid oxidation enzyme long-chain acyl-CoA dehydrogenase can be a source of mitochondrial hydrogen peroxide

Fatty acid oxidation (FAO)-driven H(2)O(2) has been shown to be a major source of oxidative stress in several tissues and disease states. Here, we established that the mitochondrial flavoprotein long-chain acyl-CoA dehydrogenase (LCAD), which catalyzes a key step in mitochondrial FAO, directly produ...

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Detalles Bibliográficos
Autores principales: Zhang, Yuxun, Bharathi, Sivakama S., Beck, Megan E., Goetzman, Eric S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597861/
https://www.ncbi.nlm.nih.gov/pubmed/31234015
http://dx.doi.org/10.1016/j.redox.2019.101253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597861/
https://www.ncbi.nlm.nih.gov/pubmed/31234015
http://dx.doi.org/10.1016/j.redox.2019.101253

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