An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2

BACKGROUND: Mutations in LRRK2 are the most common cause of autosomal dominant Parkinson's disease, and the relevance of LRRK2 to the sporadic form of the disease is becoming ever more apparent. It is therefore essential that studies are conducted to improve our understanding of the cellular ro...

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Detalles Bibliográficos
Autores principales: Connor-Robson, Natalie, Booth, Heather, Martin, Jeffrey G., Gao, Benbo, Li, Kejie, Doig, Natalie, Vowles, Jane, Browne, Cathy, Klinger, Laura, Juhasz, Peter, Klein, Christine, Cowley, Sally A., Bolam, Paul, Hirst, Warren, Wade-Martins, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597903/
https://www.ncbi.nlm.nih.gov/pubmed/30954703
http://dx.doi.org/10.1016/j.nbd.2019.04.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597903/
https://www.ncbi.nlm.nih.gov/pubmed/30954703
http://dx.doi.org/10.1016/j.nbd.2019.04.005

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