Neuropathological changes and cognitive deficits in rats transgenic for human mutant tau recapitulate human tauopathy

The assembly of tau protein into abnormal filaments and brain cell degeneration are characteristic of a number of human neurodegenerative diseases, including Alzheimer's disease and frontotemporal dementia and parkinsonism linked to chromosome 17. Several murine models have been generated to be...

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Detalles Bibliográficos
Autores principales: Malcolm, Janice C., Breuillaud, Lionel, Do Carmo, Sonia, Hall, Hélène, Welikovitch, Lindsay A., Macdonald, Jennifer A., Goedert, Michel, Cuello, A. Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597947/
https://www.ncbi.nlm.nih.gov/pubmed/30905766
http://dx.doi.org/10.1016/j.nbd.2019.03.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597947/
https://www.ncbi.nlm.nih.gov/pubmed/30905766
http://dx.doi.org/10.1016/j.nbd.2019.03.018

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