Cargando…

Neuropathological changes and cognitive deficits in rats transgenic for human mutant tau recapitulate human tauopathy

The assembly of tau protein into abnormal filaments and brain cell degeneration are characteristic of a number of human neurodegenerative diseases, including Alzheimer's disease and frontotemporal dementia and parkinsonism linked to chromosome 17. Several murine models have been generated to be...

Descripción completa

Detalles Bibliográficos
Autores principales:	Malcolm, Janice C., Breuillaud, Lionel, Do Carmo, Sonia, Hall, Hélène, Welikovitch, Lindsay A., Macdonald, Jennifer A., Goedert, Michel, Cuello, A. Claudio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597947/ https://www.ncbi.nlm.nih.gov/pubmed/30905766 http://dx.doi.org/10.1016/j.nbd.2019.03.018

Ejemplares similares

Early intraneuronal amyloid triggers neuron-derived inflammatory signaling in APP transgenic rats and human brain
por: Welikovitch, Lindsay A., et al.
Publicado: (2020)

Tauopathy-induced retinal dysfunction in the P301S mutant human tau transgenic mouse
por: Mazzaro, Nadia, et al.
Publicado: (2013)

Peripheral administration of tau aggregates triggers intracerebral tauopathy in transgenic mice
por: Clavaguera, Florence, et al.
Publicado: (2013)

VPS35 regulates tau phosphorylation and neuropathology in tauopathy
por: Vagnozzi, Alana N., et al.
Publicado: (2021)

Anterograde and Retrograde Propagation of Inoculated Human Tau Fibrils and Tau Oligomers in a Non-Transgenic Rat Tauopathy Model
por: Langer Horvat, Lea, et al.
Publicado: (2023)

Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimer’s disease and other tauopathies
por: Xia, Yuxing, et al.
Publicado: (2020)

Transmission and spreading of tauopathy in transgenic mouse brain
por: Clavaguera, Florence, et al.
Publicado: (2009)

Assembly of transgenic human P301S Tau is necessary for neurodegeneration in murine spinal cord
por: Macdonald, Jennifer A., et al.
Publicado: (2019)

Erythropoietin-derived peptide treatment reduced neurological deficit and neuropathological changes in a mouse model of tauopathy
por: Choi, Yun-Beom, et al.
Publicado: (2021)

Neuropathological criteria of anti-IgLON5-related tauopathy
por: Gelpi, Ellen, et al.
Publicado: (2016)

Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau
por: Schweighauser, Manuel, et al.
Publicado: (2023)

Colocalization of BRCA1 with Tau Aggregates in Human Tauopathies
por: Kurihara, Masanori, et al.
Publicado: (2019)

Commentary: Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic Mice
por: Betts, Matthew J., et al.
Publicado: (2018)

Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice
por: Chang, Yanmin, et al.
Publicado: (2021)

P301S Mutant Human Tau Transgenic Mice Manifest Early Symptoms of Human Tauopathies with Dementia and Altered Sensorimotor Gating
por: Takeuchi, Hiroki, et al.
Publicado: (2011)

Genetic Background Influences the Propagation of Tau Pathology in Transgenic Rodent Models of Tauopathy
por: Smolek, Tomas, et al.
Publicado: (2019)

Glucose deficit triggers tau pathology and synaptic dysfunction in a tauopathy mouse model
por: Lauretti, E, et al.
Publicado: (2017)

Corrigendum: Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice
por: Chang, Yanmin, et al.
Publicado: (2021)

A simple human cell model for TAU trafficking and tauopathy-related TAU pathology
por: Bell, Michael, et al.
Publicado: (2021)

Corrigendum: Genetic Background Influences the Propagation of Tau Pathology in Transgenic Rodent Models of Tauopathy
por: Smolek, Tomas, et al.
Publicado: (2020)

A phenotypic model recapitulating the neuropathology of Parkinson's disease
por: Ferris, Craig F, et al.
Publicado: (2013)

Transcellular Spreading of Tau in Tauopathies
por: Demaegd, Koen, et al.
Publicado: (2018)

The tauopathy associated with mutation +3 in intron 10 of Tau: characterization of the MSTD family
por: Spina, Salvatore, et al.
Publicado: (2008)

Near Infrared Light Treatment Reduces Synaptic Levels of Toxic Tau Oligomers in Two Transgenic Mouse Models of Human Tauopathies
por: Comerota, Michele M., et al.
Publicado: (2018)

Tetrandrine ameliorates cognitive deficits and mitigates tau aggregation in cell and animal models of tauopathies
por: Tong, Benjamin Chun-Kit, et al.
Publicado: (2022)

Truncated tau deregulates synaptic markers in rat model for human tauopathy
por: Jadhav, Santosh, et al.
Publicado: (2015)

Human tauopathy-derived tau strains determine the substrates recruited for templated amplification
por: Tarutani, Airi, et al.
Publicado: (2021)

Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy
por: Schaeffer, Véronique, et al.
Publicado: (2012)

Glial Tau Pathology in Tauopathies: Functional Consequences
por: Kahlson, Martha A., et al.
Publicado: (2016)

Neuropathology of Beta-propeller protein associated neurodegeneration (BPAN): a new tauopathy
por: Paudel, R., et al.
Publicado: (2015)

Passive Immunization with Phospho-Tau Antibodies Reduces Tau Pathology and Functional Deficits in Two Distinct Mouse Tauopathy Models
por: Sankaranarayanan, Sethu, et al.
Publicado: (2015)

Are Tau Aggregates Toxic or Protective in Tauopathies?
por: Cowan, Catherine M., et al.
Publicado: (2013)

NMR Studies of Tau Protein in Tauopathies
por: Kitoka, Kristine, et al.
Publicado: (2021)

Behavioral and Neuropathological Phenotyping of the Tau58/2 and Tau58/4 Transgenic Mouse Models for FTDP-17
por: Van Dam, Debby, et al.
Publicado: (2023)

Extracellular vesicles: Major actors of heterogeneity in tau spreading among human tauopathies
por: Leroux, Elodie, et al.
Publicado: (2022)

Neuroprotective effects of Cerebrolysin in triple repeat Tau transgenic model of Pick’s disease and fronto-temporal tauopathies
por: Rockenstein, Edward, et al.
Publicado: (2015)

Characterisation of tau in the human and rodent enteric nervous system under physiological conditions and in tauopathy
por: Lionnet, Arthur, et al.
Publicado: (2018)

Clinical diagnoses among individuals with primary age-related tauopathy versus Alzheimer’s neuropathology
por: Teylan, Merilee, et al.
Publicado: (2019)

Modeling Alzheimer’s disease in transgenic rats
por: Do Carmo, Sonia, et al.
Publicado: (2013)

Tau exon 10 alternative splicing and tauopathies
por: Liu, Fei, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_7stpcb6tna63mo5v9k3vhpv86c