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Neem Derivatives Inhibits Tau Aggregation(1)

Tau is a phosphoprotein with natively unfolded conformation that functions to stabilize microtubules in axons. Alzheimer’s disease pathology triggers several modifications in tau, which causes it to lose its affinity towards microtubule, thus, leading to microtubule disassembly and loss of axonal in...

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Detalles Bibliográficos
Autores principales: Gorantla, Nalini V., Das, Rashmi, Mulani, Fayaj A., Thulasiram, Hirekodathakallu V., Chinnathambi, Subashchandrabose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597962/
https://www.ncbi.nlm.nih.gov/pubmed/31259310
http://dx.doi.org/10.3233/ADR-190118