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Neem Derivatives Inhibits Tau Aggregation(1)
Tau is a phosphoprotein with natively unfolded conformation that functions to stabilize microtubules in axons. Alzheimer’s disease pathology triggers several modifications in tau, which causes it to lose its affinity towards microtubule, thus, leading to microtubule disassembly and loss of axonal in...
Autores principales: | Gorantla, Nalini V., Das, Rashmi, Mulani, Fayaj A., Thulasiram, Hirekodathakallu V., Chinnathambi, Subashchandrabose |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597962/ https://www.ncbi.nlm.nih.gov/pubmed/31259310 http://dx.doi.org/10.3233/ADR-190118 |
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