Gemfibrozil, a Lipid-Lowering Drug, Lowers Amyloid Plaque Pathology and Enhances Memory in a Mouse Model of Alzheimer’s Disease via Peroxisome Proliferator-Activated Receptor α

Deposition of extracellular senile plaques containing amyloid-β is one of the major neuropathological characteristics of Alzheimer’s disease (AD). Therefore, targeting amyloid-β dyshomeostasis is an important therapeutic strategy for treatment of AD. In this study, we demonstrate that gemfibrozil, a...

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Detalles Bibliográficos
Autores principales: Chandra, Sujyoti, Pahan, Kalipada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597963/
https://www.ncbi.nlm.nih.gov/pubmed/31259309
http://dx.doi.org/10.3233/ADR-190104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597963/
https://www.ncbi.nlm.nih.gov/pubmed/31259309
http://dx.doi.org/10.3233/ADR-190104

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