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Loss of One Engrailed1 Allele Enhances Induced α-Synucleinopathy

BACKGROUND: Parkinson’s disease (PD) is a synucleinopathy that has multiple neuropathological characteristics, with nigrostriatal dopamine system degeneration being a core feature. Current models of PD pathology typically fail to recapitulate several attributes of the pathogenic process and neuropat...

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Detalles Bibliográficos
Autores principales: Chatterjee, Diptaman, Sanchez, Daniel Saiz, Quansah, Emmanuel, Rey, Nolwen L., George, Sonia, Becker, Katelyn, Madaj, Zachary, Steiner, Jennifer A., Ma, Jiyan, Escobar Galvis, Martha L., Kordower, Jeffrey H., Brundin, Patrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597991/
https://www.ncbi.nlm.nih.gov/pubmed/30932894
http://dx.doi.org/10.3233/JPD-191590