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Gefitinib-coated balloon inhibits the excessive hyperplasia of intima after vascular injuries through PI3K/AKT pathway

OBJECTIVE: To explore the effect of gefitinib-coated balloon suppressive action on the excessive hyperplasia of intima after balloon injury of common carotid artery in rats and on the PI3K/AKT signal pathway. METHODS: MTT method and the expression of Bcl-2 and Caspase-3 proteins were detected in vit...

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Detalles Bibliográficos
Autores principales: Tang, Fen, Liu, Maojun, Zeng, Ou, Tan, Wenting, Long, Junrong, Liu, Shengquan, Yang, Jun, Chu, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598000/
https://www.ncbi.nlm.nih.gov/pubmed/31045551
http://dx.doi.org/10.3233/THC-199031