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Progressive Impairment of NK Cell Cytotoxic Degranulation Is Associated With TGF-β1 Deregulation and Disease Progression in Pancreatic Cancer

Natural killer (NK) cells are key effectors in cancer immunosurveillance and can be used as a prognostic biomarker in diverse cancers. Nonetheless, the role of NK cells in pancreatic cancer (PC) remains elusive, given conflicting data on their association with disease prognosis. In this study, using...

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Detalles Bibliográficos
Autores principales: Jun, Eunsung, Song, Ah Young, Choi, Ji-Wan, Lee, Hyeon Ho, Kim, Mi-Yeon, Ko, Dae-Hyun, Kang, Hyo Jeong, Kim, Seong Who, Bryceson, Yenan, Kim, Song Cheol, Kim, Hun Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598013/
https://www.ncbi.nlm.nih.gov/pubmed/31281312
http://dx.doi.org/10.3389/fimmu.2019.01354