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The genetics of isolated and syndromic clubfoot

PURPOSE: Congenital clubfoot is a serious birth defect that affects nearly 0.1% of all births. Though there is strong evidence for a genetic basis of isolated clubfoot, aside from a handful of associations, much of the heritability remains unexplained. METHODS: By systematically examining the genes...

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Detalles Bibliográficos
Autores principales: Sadler, B., Gurnett, C. A., Dobbs, M. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598048/
https://www.ncbi.nlm.nih.gov/pubmed/31312262
http://dx.doi.org/10.1302/1863-2548.13.190063