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7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects

[Image: see text] Mitragyna speciosa, more commonly known as kratom, is a plant native to Southeast Asia, the leaves of which have been used traditionally as a stimulant, analgesic, and treatment for opioid addiction. Recently, growing use of the plant in the United States and concerns that kratom r...

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Detalles Bibliográficos
Autores principales: Kruegel, Andrew C., Uprety, Rajendra, Grinnell, Steven G., Langreck, Cory, Pekarskaya, Elizabeth A., Le Rouzic, Valerie, Ansonoff, Michael, Gassaway, Madalee M., Pintar, John E., Pasternak, Gavril W., Javitch, Jonathan A., Majumdar, Susruta, Sames, Dalibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598159/
https://www.ncbi.nlm.nih.gov/pubmed/31263758
http://dx.doi.org/10.1021/acscentsci.9b00141