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Evaluation of the bioavailability of hydrocortisone when prepared as solid dispersion

This study was conducted to formulate, characterize, and investigate the bioavailability of hydrocortisone (HCT) when prepared as solid dispersions. HCT was mixed in an organic solvent with polyethylene glycol 4000 (PEG 4000) and Kolliphor® P 407. Spray drying technique was employed to form a solid...

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Detalles Bibliográficos
Autores principales: Altamimi, Mohammad A., Elzayat, Ehab M., Qamar, Wajhul, Alshehri, Sultan M., Sherif, Abdelrahman Y., Haq, Nazrul, Shakeel, Faiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598222/
https://www.ncbi.nlm.nih.gov/pubmed/31297016
http://dx.doi.org/10.1016/j.jsps.2019.03.004