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Macrophage galactose-type lectin (MGL) is induced on M2 microglia and participates in the resolution phase of autoimmune neuroinflammation

BACKGROUND: Multiple sclerosis (MS) involves a misdirected immune attack against myelin in the brain and spinal cord, leading to profound neuroinflammation and neurodegeneration. While the mechanisms of disease pathogenesis have been widely studied, the suppression mechanisms that lead to the resolu...

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Detalles Bibliográficos
Autores principales: Ilarregui, Juan M., Kooij, Gijs, Rodríguez, Ernesto, van der Pol, Susanne M. A., Koning, Nathalie, Kalay, Hakan, van der Horst, Joost C., van Vliet, Sandra J., García-Vallejo, Juan J., de Vries, Helga E., van Kooyk, Yvette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598247/
https://www.ncbi.nlm.nih.gov/pubmed/31248427
http://dx.doi.org/10.1186/s12974-019-1522-4