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Macrophage galactose-type lectin (MGL) is induced on M2 microglia and participates in the resolution phase of autoimmune neuroinflammation
BACKGROUND: Multiple sclerosis (MS) involves a misdirected immune attack against myelin in the brain and spinal cord, leading to profound neuroinflammation and neurodegeneration. While the mechanisms of disease pathogenesis have been widely studied, the suppression mechanisms that lead to the resolu...
Autores principales: | Ilarregui, Juan M., Kooij, Gijs, Rodríguez, Ernesto, van der Pol, Susanne M. A., Koning, Nathalie, Kalay, Hakan, van der Horst, Joost C., van Vliet, Sandra J., García-Vallejo, Juan J., de Vries, Helga E., van Kooyk, Yvette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598247/ https://www.ncbi.nlm.nih.gov/pubmed/31248427 http://dx.doi.org/10.1186/s12974-019-1522-4 |
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