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Gene expression signature of atypical breast hyperplasia and regulation by SFRP1

BACKGROUND: Atypical breast hyperplasias (AH) have a 10-year risk of progression to invasive cancer estimated at 4–7%, with the overall risk of developing breast cancer increased by ~ 4-fold. AH lesions are estrogen receptor alpha positive (ERα+) and represent risk indicators and/or precursor lesion...

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Detalles Bibliográficos
Autores principales: Gregory, Kelly J., Roberts, Amy L., Conlon, Erin M., Mayfield, Jacob A., Hagen, Mary J., Crisi, Giovanna M., Bentley, Brooke A., Kane, Jeffrey J., Makari-Judson, Grace, Mason, Holly S., Yu, Jun, Zhu, Lihua Julie, Simin, Karl, Johnson, Jacob P. S., Khan, Ashraf, Schneider, Ben R., Schneider, Sallie S., Jerry, D. Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598287/
https://www.ncbi.nlm.nih.gov/pubmed/31248446
http://dx.doi.org/10.1186/s13058-019-1157-5