Synaptic and memory dysfunction induced by tau oligomers is rescued by up-regulation of the nitric oxide cascade

BACKGROUND: Soluble aggregates of oligomeric forms of tau protein (oTau) have been associated with impairment of synaptic plasticity and memory in Alzheimer’s disease. However, the molecular mechanisms underlying the synaptic and memory dysfunction induced by elevation of oTau are still unknown. MET...

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Detalles Bibliográficos
Autores principales: Acquarone, Erica, Argyrousi, Elentina K., van den Berg, Manon, Gulisano, Walter, Fà, Mauro, Staniszewski, Agnieszka, Calcagno, Elisa, Zuccarello, Elisa, D’Adamio, Luciano, Deng, Shi-Xian, Puzzo, Daniela, Arancio, Ottavio, Fiorito, Jole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598340/
https://www.ncbi.nlm.nih.gov/pubmed/31248451
http://dx.doi.org/10.1186/s13024-019-0326-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598340/
https://www.ncbi.nlm.nih.gov/pubmed/31248451
http://dx.doi.org/10.1186/s13024-019-0326-4

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