Therapeutic Bispecific T-Cell Engager Antibody Targeting the Transferrin Receptor

Bispecific T-cell engager antibodies (BiTE) have been explored as a means to recruit cytolytic T cells to kill tumor cells. The transferrin receptor (TfR) is highly expressed on the surface of rapidly proliferating tumor cells. Therefore, it holds great potential in T cell redirecting therapies. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Fu, Mingpeng, He, Qi, Guo, Zilong, Zhou, Xiaoran, Li, Heli, Zhao, Liang, Tang, Hongling, Zhou, Xiaoqi, Zhu, Huifen, Shen, Guanxin, He, Yong, Lei, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598450/
https://www.ncbi.nlm.nih.gov/pubmed/31293575
http://dx.doi.org/10.3389/fimmu.2019.01396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598450/
https://www.ncbi.nlm.nih.gov/pubmed/31293575
http://dx.doi.org/10.3389/fimmu.2019.01396

Ejemplares similares