Activation of human α-carbonic anhydrase isoforms I, II, IV and VII with bis-histamine schiff bases and bis-spinaceamine substituted derivatives

A series of histamine bis-Schiff bases and bis-spinaceamine derivatives were synthesised and investigated as activators of four human (h) carbonic anhydrase (CA, EC 4.2.1.1) isoforms, the cytosolic hCA I, II and VII, and the membrane-associated hCA IV. All isoforms were effectively activated by the...

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Detalles Bibliográficos
Autores principales: Akocak, Suleyman, Lolak, Nabih, Bua, Silvia, Nocentini, Alessio, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598482/
https://www.ncbi.nlm.nih.gov/pubmed/31237157
http://dx.doi.org/10.1080/14756366.2019.1630616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598482/
https://www.ncbi.nlm.nih.gov/pubmed/31237157
http://dx.doi.org/10.1080/14756366.2019.1630616

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