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Appraisal of anti-protozoan activity of nitroaromatic benzenesulfonamides inhibiting carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani

Chagas disease and leishmaniasis are neglected tropical disorders caused by the protozoans Trypanosoma cruzi and Leishmania spp. Carbonic anhydrases (CAs, EC 4.2.1.1) from these protozoans (α-TcCA and β-LdcCA) have been validated as promising targets for chemotherapic interventions. Many anti-protoz...

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Detalles Bibliográficos
Autores principales: Nocentini, Alessio, Osman, Sameh M., Rodrigues, Igor A., Cardoso, Veronica S., Alasmary, Fatmah Ali S., AlOthman, Zeid, Vermelho, Alane B., Gratteri, Paola, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598531/
https://www.ncbi.nlm.nih.gov/pubmed/31219348
http://dx.doi.org/10.1080/14756366.2019.1626375