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Synthesis of a new series of 3-functionalised-1-phenyl-1,2,3-triazole sulfamoylbenzamides as carbonic anhydrase I, II, IV and IX inhibitors

The synthesis of a novel series of 3-functionalised benzenesulfonamides incorporating phenyl-1,2,3-triazole with an amide linker was achieved by using the “click-tail” approach. The new compounds, including the intermediates, were assayed as inhibitors of human carbonic anhydrase (CA, EC 4.2.1.1) is...

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Detalles Bibliográficos
Autores principales: Swain, Baijayantimala, Angeli, Andrea, Angapelly, Srinivas, Thacker, Pavitra S., Singh, Priti, Supuran, Claudiu T., Arifuddin, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598542/
https://www.ncbi.nlm.nih.gov/pubmed/31237458
http://dx.doi.org/10.1080/14756366.2019.1629432