Liquisolid pellets: A pharmaceutical technology strategy to improve the dissolution rate of ritonavir

Liquisolid pellets (LPs) prepared by extrusion-spheronization are promising delivery systems to improve the dissolution rate of poorly water-soluble drugs. However, developing LPs for high dose drugs (e.g. antiretroviral ritonavir, RTV) is a major challenge due to technical and quality constraints....

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Detalles Bibliográficos
Autores principales: De Espíndola, Brenda, Beringhs, André O'Reilly, Sonaglio, Diva, Stulzer, Hellen Karine, Silva, Marcos Antônio Segatto, Ferraz, Humberto Gomes, Pezzini, Bianca Ramos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598603/
https://www.ncbi.nlm.nih.gov/pubmed/31297025
http://dx.doi.org/10.1016/j.jsps.2019.04.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598603/
https://www.ncbi.nlm.nih.gov/pubmed/31297025
http://dx.doi.org/10.1016/j.jsps.2019.04.005

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