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Liquisolid pellets: A pharmaceutical technology strategy to improve the dissolution rate of ritonavir
Liquisolid pellets (LPs) prepared by extrusion-spheronization are promising delivery systems to improve the dissolution rate of poorly water-soluble drugs. However, developing LPs for high dose drugs (e.g. antiretroviral ritonavir, RTV) is a major challenge due to technical and quality constraints....
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598603/ https://www.ncbi.nlm.nih.gov/pubmed/31297025 http://dx.doi.org/10.1016/j.jsps.2019.04.005 |