Vinylphosphonites for Staudinger-induced chemoselective peptide cyclization and functionalization

In this paper, we introduce vinylphosphonites for chemoselective Staudinger-phosphonite reactions (SPhR) with azides to form vinylphosphonamidates for the subsequent modification of cysteine residues in peptides and proteins. An electron-rich alkene is turned into an electron-deficient vinylphosphon...

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Detalles Bibliográficos
Autores principales: Kasper, Marc-André, Glanz, Maria, Oder, Andreas, Schmieder, Peter, von Kries, Jens P., Hackenberger, Christian P. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598645/
https://www.ncbi.nlm.nih.gov/pubmed/31341586
http://dx.doi.org/10.1039/c9sc01345h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598645/
https://www.ncbi.nlm.nih.gov/pubmed/31341586
http://dx.doi.org/10.1039/c9sc01345h

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