Hydrogels Embedded With Melittin and Tobramycin Are Effective Against Pseudomonas aeruginosa Biofilms in an Animal Wound Model

We demonstrate that the antimicrobial peptide, melittin, is effective alone and in combination with the aminoglycosides tobramycin to kill Pseudomonas aeruginosa growing as biofilms both in vitro and in vivo. Melittin and tobramycin show enhanced in vitro activity in combination at micromolar concen...

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Detalles Bibliográficos
Autores principales: Maiden, Michael M., Zachos, Mitchell P., Waters, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598697/
https://www.ncbi.nlm.nih.gov/pubmed/31293530
http://dx.doi.org/10.3389/fmicb.2019.01348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598697/
https://www.ncbi.nlm.nih.gov/pubmed/31293530
http://dx.doi.org/10.3389/fmicb.2019.01348

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