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Solvent-dependent segmental dynamics in intrinsically disordered proteins

Protein and water dynamics have a synergistic relationship, which is particularly important for intrinsically disordered proteins (IDPs), although the details of this coupling remain poorly understood. Here, we combine temperature-dependent molecular dynamics simulations using different water models...

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Detalles Bibliográficos
Autores principales: Salvi, Nicola, Abyzov, Anton, Blackledge, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598773/
https://www.ncbi.nlm.nih.gov/pubmed/31259246
http://dx.doi.org/10.1126/sciadv.aax2348