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Tubular NOX4 expression decreases in chronic kidney disease but does not modify fibrosis evolution

BACKGROUND: NADPH oxidase 4 (NOX4) catalyzes the formation of hydrogen peroxide (H(2)O(2)). NOX4 is highly expressed in the kidney, but its role in renal injury is unclear and may depend on its specific tissue localization. METHODS: We performed immunostaining with a specific anti-NOX4 antibody and...

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Detalles Bibliográficos
Autores principales: Rajaram, Renuga Devi, Dissard, Romain, Faivre, Anna, Ino, Frédérique, Delitsikou, Vasiliki, Jaquet, Vincent, Cagarelli, Thomas, Lindenmeyer, Maja, Jansen-Duerr, Pidder, Cohen, Clemens, Moll, Solange, de Seigneux, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598841/
https://www.ncbi.nlm.nih.gov/pubmed/31247506
http://dx.doi.org/10.1016/j.redox.2019.101234