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Conserved transcriptomic profile between mouse and human colitis allows unsupervised patient stratification

Clinical manifestations and response to therapies in ulcerative colitis (UC) are heterogeneous, yet patient classification criteria for tailored therapies are currently lacking. Here, we present an unsupervised molecular classification of UC patients, concordant with response to therapy in independe...

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Detalles Bibliográficos
Autores principales: Czarnewski, Paulo, Parigi, Sara M., Sorini, Chiara, Diaz, Oscar E., Das, Srustidhar, Gagliani, Nicola, Villablanca, Eduardo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598981/
https://www.ncbi.nlm.nih.gov/pubmed/31253778
http://dx.doi.org/10.1038/s41467-019-10769-x