DNA double-strand breaks in telophase lead to coalescence between segregated sister chromatid loci

DNA double strand breaks (DSBs) pose a high risk for genome integrity. Cells repair DSBs through homologous recombination (HR) when a sister chromatid is available. HR is upregulated by the cycling dependent kinase (CDK) despite the paradox of telophase, where CDK is high but a sister chromatid is n...

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Detalles Bibliográficos
Autores principales: Ayra-Plasencia, Jessel, Machín, Félix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598993/
https://www.ncbi.nlm.nih.gov/pubmed/31253793
http://dx.doi.org/10.1038/s41467-019-10742-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598993/
https://www.ncbi.nlm.nih.gov/pubmed/31253793
http://dx.doi.org/10.1038/s41467-019-10742-8

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