Cargando…
DNA double-strand breaks in telophase lead to coalescence between segregated sister chromatid loci
DNA double strand breaks (DSBs) pose a high risk for genome integrity. Cells repair DSBs through homologous recombination (HR) when a sister chromatid is available. HR is upregulated by the cycling dependent kinase (CDK) despite the paradox of telophase, where CDK is high but a sister chromatid is n...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598993/ https://www.ncbi.nlm.nih.gov/pubmed/31253793 http://dx.doi.org/10.1038/s41467-019-10742-8 |