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Marrying chemistry with biology by combining on-chip solution-based combinatorial synthesis and cellular screening
Drug development often relies on high-throughput cell-based screening of large compound libraries. However, the lack of miniaturized and parallelized methodologies in chemistry as well as strict separation and incompatibility of the synthesis of bioactive compounds from their biological screenings m...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599004/ https://www.ncbi.nlm.nih.gov/pubmed/31253767 http://dx.doi.org/10.1038/s41467-019-10685-0 |