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Conventional and Specific-Pathogen Free Rats Respond Differently to Anesthesia and Surgical Trauma
Specific-pathogen free (SPF) animals were introduced in the 1960s to minimize disease and infection as variables in biomedical research. Our aim was to examine differences in physiological response in rat colonies bred and housed in a conventional versus SPF facility, and implications for research....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599031/ https://www.ncbi.nlm.nih.gov/pubmed/31253875 http://dx.doi.org/10.1038/s41598-019-45871-z |