Cargando…

Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases

Understanding how immune challenges elicit different responses is critical for diagnosing and deciphering immune regulation. Using a modular strategy to interpret the complex transcriptional host response in mouse models of infection and inflammation, we show a breadth of immune responses in the lun...

Descripción completa

Detalles Bibliográficos
Autores principales: Singhania, Akul, Graham, Christine M., Gabryšová, Leona, Moreira-Teixeira, Lúcia, Stavropoulos, Evangelos, Pitt, Jonathan M., Chakravarty, Probir, Warnatsch, Annika, Branchett, William J., Conejero, Laura, Lin, Jing-Wen, Davidson, Sophia, Wilson, Mark S., Bancroft, Gregory, Langhorne, Jean, Frickel, Eva, Sesay, Abdul K., Priestnall, Simon L., Herbert, Eleanor, Ioannou, Marianna, Wang, Qian, Humphreys, Ian R., Dodd, Jonathan, Openshaw, Peter J. M., Mayer-Barber, Katrin D., Jankovic, Dragana, Sher, Alan, Lloyd, Clare M., Baldwin, Nicole, Chaussabel, Damien, Papayannopoulos, Venizelos, Wack, Andreas, Banchereau, Jacques F., Pascual, Virginia M., O’Garra, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599044/
https://www.ncbi.nlm.nih.gov/pubmed/31253760
http://dx.doi.org/10.1038/s41467-019-10601-6