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Polyhistidine facilitates direct membrane translocation of cell-penetrating peptides into cells

The bovine lactoferricin L6 (RRWQWR) has been previously identified as a novel cell-penetrating peptide (CPP) that is able to efficiently internalize into human cells. L6 interacts with quantum dots (QDs) noncovalently to generate stable L6/QD complexes that enter cells by endocytosis. In this study...

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Detalles Bibliográficos
Autores principales: Lee, Han-Jung, Huang, Yue-Wern, Chiou, Shiow-Her, Aronstam, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599048/
https://www.ncbi.nlm.nih.gov/pubmed/31253836
http://dx.doi.org/10.1038/s41598-019-45830-8