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Manassantin B shows antiviral activity against coxsackievirus B3 infection by activation of the STING/TBK-1/IRF3 signalling pathway

Coxsackievirus B3 (CVB3) is an important human pathogen associated with the development of acute pancreatitis, myocarditis, and type 1 diabetes. Currently, no vaccines or antiviral therapeutics are approved for the prevention and treatment of CVB3 infection. We found that Saururus chinensis Baill ex...

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Detalles Bibliográficos
Autores principales: Song, Jae-Hyoung, Ahn, Jae-Hee, Kim, Seong-Ryeol, Cho, Sungchan, Hong, Eun-Hye, Kwon, Bo-Eun, Kim, Dong-eun, Choi, Miri, Choi, Hwa-Jung, Cha, Younggil, Chang, Sun-Young, Ko, Hyun-Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599049/
https://www.ncbi.nlm.nih.gov/pubmed/31253850
http://dx.doi.org/10.1038/s41598-019-45868-8