Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses

The magnitude of T cell responses to infection is a function of the naïve T cell repertoire combined with the context and duration of antigen presentation. Using mass spectrometry, we identify and quantify 21 class 1 MHC-restricted influenza A virus (IAV)-peptides following either direct or cross-pr...

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Detalles Bibliográficos
Autores principales: Wu, Ting, Guan, Jing, Handel, Andreas, Tscharke, David C., Sidney, John, Sette, Alessandro, Wakim, Linda M., Sng, Xavier Y. X., Thomas, Paul G., Croft, Nathan P., Purcell, Anthony W., La Gruta, Nicole L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599079/
https://www.ncbi.nlm.nih.gov/pubmed/31253788
http://dx.doi.org/10.1038/s41467-019-10661-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599079/
https://www.ncbi.nlm.nih.gov/pubmed/31253788
http://dx.doi.org/10.1038/s41467-019-10661-8

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