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Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse

The T cell immune synapse is a site of intense vesicular trafficking. Here we show that the golgin GMAP210, known to capture vesicles and organize membrane traffic at the Golgi, is involved in the vesicular transport of LAT to the immune synapse. Upon activation, more GMAP210 interact with LAT-conta...

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Detalles Bibliográficos
Autores principales: Zucchetti, Andres Ernesto, Bataille, Laurence, Carpier, Jean-Marie, Dogniaux, Stéphanie, San Roman-Jouve, Mabel, Maurin, Mathieu, Stuck, Michael W., Rios, Rosa M., Baldari, Cosima T., Pazour, Gregory J., Hivroz, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599081/
https://www.ncbi.nlm.nih.gov/pubmed/31253807
http://dx.doi.org/10.1038/s41467-019-10891-w