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TLR11-independent inflammasome activation is critical for CD4+ T cell-derived IFN-γ production and host resistance to Toxoplasma gondii

Innate recognition of invading intracellular pathogens is essential for regulating robust and rapid CD4+ T cell effector function, which is critical for host-mediated immunity. The intracellular apicomplexan parasite, Toxoplasma gondii, is capable of infecting almost any nucleated cell of warm-blood...

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Detalles Bibliográficos
Autores principales: López-Yglesias, Américo H., Camanzo, Ellie, Martin, Andrew T., Araujo, Alessandra M., Yarovinsky, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599108/
https://www.ncbi.nlm.nih.gov/pubmed/31194844
http://dx.doi.org/10.1371/journal.ppat.1007872