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Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye
Innovative protein engineering and chemical conjugation technologies have yielded an impressive number of drug candidates in clinical development including >80 antibody drug conjugates, >60 bispecific antibodies, >35 Fc-fusion proteins and >10 immuno-cytokines. Despite these innovations,...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599134/ https://www.ncbi.nlm.nih.gov/pubmed/31251757 http://dx.doi.org/10.1371/journal.pone.0218613 |