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Atomic view into Plasmodium actin polymerization, ATP hydrolysis, and fragmentation

Plasmodium actins form very short filaments and have a noncanonical link between ATP hydrolysis and polymerization. Long filaments are detrimental to the parasites, but the structural factors constraining Plasmodium microfilament lengths have remained unknown. Using high-resolution crystallography,...

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Detalles Bibliográficos
Autores principales: Kumpula, Esa-Pekka, Lopez, Andrea J., Tajedin, Leila, Han, Huijong, Kursula, Inari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599135/
https://www.ncbi.nlm.nih.gov/pubmed/31199804
http://dx.doi.org/10.1371/journal.pbio.3000315