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The insulin-like growth factor 2 gene in mammals: Organizational complexity within a conserved locus

The secreted protein, insulin-like growth factor 2 (IGF2), plays a central role in fetal and prenatal growth and development, and is regulated at the genetic level by parental imprinting, being expressed predominantly from the paternally derived chromosome in mice and humans. Here, IGF2/Igf2 and its...

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Detalles Bibliográficos
Autores principales: Baral, Kabita, Rotwein, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599137/
https://www.ncbi.nlm.nih.gov/pubmed/31251794
http://dx.doi.org/10.1371/journal.pone.0219155