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Robotic assisted generation of 2′-deoxy-2′-fluoro-modifed RNA aptamers – High performance enabling strategies in aptamer selection

Aptamer selection is a laborious procedure, requiring expertise and significant resources. These characteristics limit the accessibility of researchers to these molecular tools. We describe a selection procedure, making use of a robotic system that allows the fully automated selection of RNA and 2′d...

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Detalles Bibliográficos
Autores principales: Breuers, Stefan, Bryant, Laura Lledo, Legen, Tjasa, Mayer, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599171/
https://www.ncbi.nlm.nih.gov/pubmed/31152781
http://dx.doi.org/10.1016/j.ymeth.2019.05.022