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Disruption of Foxg1 impairs neural plasticity leading to social and cognitive behavioral defects

The transcription factor Foxg1 is known to be continuously expressed at a high level in mature neurons in the telencephalon, but little is known about its role in neural plasticity. Mutations in human FOXG1 cause deficiencies in learning and memory and limit social ability, which is defined as FOXG1...

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Detalles Bibliográficos
Autores principales: Yu, Baocong, Liu, Junhua, Su, Mingzhao, Wang, Chunlian, Chen, Huanxin, Zhao, Chunjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599246/
https://www.ncbi.nlm.nih.gov/pubmed/31253171
http://dx.doi.org/10.1186/s13041-019-0484-x