Cargando…
Disruption of Foxg1 impairs neural plasticity leading to social and cognitive behavioral defects
The transcription factor Foxg1 is known to be continuously expressed at a high level in mature neurons in the telencephalon, but little is known about its role in neural plasticity. Mutations in human FOXG1 cause deficiencies in learning and memory and limit social ability, which is defined as FOXG1...
Autores principales: | Yu, Baocong, Liu, Junhua, Su, Mingzhao, Wang, Chunlian, Chen, Huanxin, Zhao, Chunjie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599246/ https://www.ncbi.nlm.nih.gov/pubmed/31253171 http://dx.doi.org/10.1186/s13041-019-0484-x |
Ejemplares similares
-
FOXG1 sequentially orchestrates subtype specification of postmitotic
cortical projection neurons
por: Liu, Junhua, et al.
Publicado: (2022) -
Loss of Calretinin in L5a impairs the formation of the barrel cortex leading to abnormal whisker-mediated behaviors
por: Su, Mingzhao, et al.
Publicado: (2021) -
Brpf1 Haploinsufficiency Impairs Dendritic Arborization and Spine Formation, Leading to Cognitive Deficits
por: Su, Yan, et al.
Publicado: (2019) -
Foxg1 deletion impairs the development of the epithalamus
por: Liu, Bin, et al.
Publicado: (2018) -
Forced Expression of Foxg1 in the Cortical Hem Leads to the Transformation of Cajal-Retzius Cells into Dentate Granule Neurons
por: Liu, Bin, et al.
Publicado: (2018)