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Prostaglandin receptor EP4 expression by Th17 cells is associated with high disease activity in ankylosing spondylitis
BACKGROUND: Th17 cells are involved in the pathogenesis of ankylosing spondylitis (AS). However, the mechanism underlying enhanced Th17 cell accumulation in AS remains unknown. The prostaglandin E(2) receptor EP2/EP4 signaling pathway plays a critical role in the development of autoimmune Th17 cells...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599260/ https://www.ncbi.nlm.nih.gov/pubmed/31253169 http://dx.doi.org/10.1186/s13075-019-1948-1 |