Human amyloid-β enriched extracts: evaluation of in vitro and in vivo internalization and molecular characterization

BACKGROUND: Intracerebral inoculation of extracts from post-mortem human Alzheimer’s disease brains into mice produces a prion-like spreading effect of amyloid-β. The differences observed between these extracts and the synthetic peptide, in terms of amyloid-β internalization and seed and cell-to-cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Pedrero-Prieto, Cristina M., Flores-Cuadrado, Alicia, Saiz-Sánchez, Daniel, Úbeda-Bañón, Isabel, Frontiñán-Rubio, Javier, Alcaín, Francisco J., Mateos-Hernández, Lourdes, de la Fuente, José, Durán-Prado, Mario, Villar, Margarita, Martínez-Marcos, Alino, Peinado, Juan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599264/
https://www.ncbi.nlm.nih.gov/pubmed/31253170
http://dx.doi.org/10.1186/s13195-019-0513-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599264/
https://www.ncbi.nlm.nih.gov/pubmed/31253170
http://dx.doi.org/10.1186/s13195-019-0513-0

Ejemplares similares