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Human amyloid-β enriched extracts: evaluation of in vitro and in vivo internalization and molecular characterization

BACKGROUND: Intracerebral inoculation of extracts from post-mortem human Alzheimer’s disease brains into mice produces a prion-like spreading effect of amyloid-β. The differences observed between these extracts and the synthetic peptide, in terms of amyloid-β internalization and seed and cell-to-cel...

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Detalles Bibliográficos
Autores principales:	Pedrero-Prieto, Cristina M., Flores-Cuadrado, Alicia, Saiz-Sánchez, Daniel, Úbeda-Bañón, Isabel, Frontiñán-Rubio, Javier, Alcaín, Francisco J., Mateos-Hernández, Lourdes, de la Fuente, José, Durán-Prado, Mario, Villar, Margarita, Martínez-Marcos, Alino, Peinado, Juan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599264/ https://www.ncbi.nlm.nih.gov/pubmed/31253170 http://dx.doi.org/10.1186/s13195-019-0513-0

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