Single cell RNA-Seq reveals pre-cDCs fate determined by transcription factor combinatorial dose

BACKGROUND: Classic dendritic cells (cDCs) play a central role in the immune system by processing and presenting antigens to activate T cells, and consist of two major subsets: CD141(+) cDC (cDC1) and CD1c(+) cDC (cDC2). A population of migratory precursor cells, the pre-cDCs, is the immediate precu...

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Detalles Bibliográficos
Autores principales: Ma, Wenji, Lee, Jaeyop, Backenroth, Daniel, Zhou, Yu Jerry, Bush, Erin, Sims, Peter, Liu, Kang, Shen, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599345/
https://www.ncbi.nlm.nih.gov/pubmed/31253076
http://dx.doi.org/10.1186/s12860-019-0199-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599345/
https://www.ncbi.nlm.nih.gov/pubmed/31253076
http://dx.doi.org/10.1186/s12860-019-0199-y

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