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Single cell RNA-Seq reveals pre-cDCs fate determined by transcription factor combinatorial dose
BACKGROUND: Classic dendritic cells (cDCs) play a central role in the immune system by processing and presenting antigens to activate T cells, and consist of two major subsets: CD141(+) cDC (cDC1) and CD1c(+) cDC (cDC2). A population of migratory precursor cells, the pre-cDCs, is the immediate precu...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599345/ https://www.ncbi.nlm.nih.gov/pubmed/31253076 http://dx.doi.org/10.1186/s12860-019-0199-y |