In silico analysis of missense mutations in exons 1–5 of the F9 gene that cause hemophilia B

BACKGROUND: Missense mutations in the first five exons of F9, which encodes factor FIX, represent 40% of all mutations that cause hemophilia B. To address the ongoing debate regarding in silico identification of disease-causing mutations at these exons, we analyzed 215 missense mutations from www.fa...

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Detalles Bibliográficos
Autores principales: Meléndez-Aranda, Lennon, Jaloma-Cruz, Ana Rebeca, Pastor, Nina, Romero-Prado, Marina María de Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599346/
https://www.ncbi.nlm.nih.gov/pubmed/31253089
http://dx.doi.org/10.1186/s12859-019-2919-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599346/
https://www.ncbi.nlm.nih.gov/pubmed/31253089
http://dx.doi.org/10.1186/s12859-019-2919-x

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